The new sensors see. How the DNA works in living cells.

“Conceptual illustration of the bidirectional quantitative scattering microscope, which detects both forward and backwards scattered light from cells. This dual detection enables visualisation of structures ranging from whole-cell morphology to nanoscale particles. Credit: Horie et al 2025” (ScitechDaily, “Great Unified Microscope” Reveals Hidden Micro and Nano Worlds Inside Living Cells)

The major problem with all sensors, from satellites to microscopes, is. How to connect an extreme accuracy and large-area scanning? The answer can be that the same satellite, or another system, can have a wide-angle scanner and a scanner that uses highly accurate zoom. The system can also have a zoom objective that increases the zoom when the system detects something interesting. 

The new microscope uncovers the hidden world in living cells. This system can enable the control of biological processes in living cells. With incredible accuracy. The ability to control systems and their processes requires that the system observe what happens within itself. The new sensor. Called the great unified microscope, makes it possible to see into a living cell. The new system includes quantitative phase microscopy (QPM). This microscope uses forward-scattered light to detect structures at the microscale (in this study, over 100 nanometers), but it cannot access much smaller features. QPM is normally used to take images of the complex cell structure. 

Another sensor called “interferometric scattering (iSCAT) microscopy takes a different approach by relying on back-scattered light and can pick up structures as tiny as single proteins. This makes it powerful for “tracking” individual particles and following rapid changes inside cells, but it does not offer the broad, whole-cell perspective that QPM provides.” 

(ScitechDaily, “Great Unified Microscope” Reveals Hidden Micro and Nano Worlds Inside Living Cells)

The system that uses both of those sensors. The QPM and iSCAT can handle cells better. The larger area scanner searches the interesting parts of the cells. An extremely accurate scanner observes single points. With high accuracy. 

“DNA Molecule Genetic Mutation A breakthrough live-cell sensor makes DNA repair visible as it happens, unlocking new possibilities in biology and medicine. Credit: Shutterstock. A new DNA damage sensor allows scientists to watch repair unfold in living cells with unprecedented clarity” (ScitechDaily, This New Sensor Shows DNA Repair in Real Time)

The third way is to use DNA bites as the scanners. The scanner system works like old-time gramophones. The cut DNA bite follows the surface, and the system follows how the form changes in the DNA. Another version. It is to use lasers. To follow how the DNA moves when the scanner pulls it above the structure. The new systems make it possible to see. 

How does DNA fix its errors in living cells? This makes it possible. To create new innovations in biotechnology. The ability to observe certain points in the DNA. It makes it possible. To include new base pairs or remove some other base pairs with incredible accuracy. These kinds of things are the tools. These are required for the new types of genetic engineering. 

https://scitechdaily.com/great-unified-microscope-reveals-hidden-micro-and-nano-worlds-inside-living-cells/

https://scitechdaily.com/this-new-sensor-shows-dna-repair-in-real-time-video/

Thought about two abandoned houses

Kimmo Huosionmaa

In this text is only thinking, why some person works so no rational way, than in those pictures is done. Why somebody repairs the house, and then leave it empty? And why somebody hates milestones? Those questions might be interested some historians, and here I must say, that the purpose of this text is not to play some Sherlock Holmes. There is no mentioned that in those houses have done any criminal activities. So I just walked near them, and those houses interested me.


At the picture above this text is a picture of the house, and as you might see, this house is abandoned. The reason, why I write this text is, why the roof has got new sheets? When the owner of this house has left somewhere, this person has put new sheets on the roof and then abandoned this house.


The question is, why did this person do that thing? Did this person have too much money, or why this house got the new roof before abandoned? When the normal person leaves the house, is very unusual that the roof would be repaired. And there is something more about this house because there is another house near the first one, why does is didn’t get stainless plates on the roof?

If those houses have been abandoned at the same time, why only another has got stainless steel sheet. Another house has rusty plates on the roof, and that house is also abandoned, but if we think this group of houses carefully, the bigger one is, of course, the main building, but why those stainless steel plates have been put on the smaller one.


This text is only thinking about those houses, and at the second photograph is the milestone, what is destroyed. The reason for the destruction might be something like the sledgehammer, and the destruction might be made for the purpose. But who hates milestones? This is the very good question because those things are quite expensive. And if somebody sees that action, would that interested by police. But those houses are empty, and I was writing this text only for thinking, why those repairs are made just before leaving.

https://crisisofdemocracticstates.blogspot.fi/

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The rebellion of the robots can set entire civilization in danger

Artist's impression of interstellar ramjet
(Picture 1)

Kimmo Huosionmaa

This is the writing about the situation, where robots would become dangerous for the human race. Those robots might be created by mankind, and they could be some space probes, what would be sent to another star in distant future. Those probes would lose contact with Earth and it would make the terrible situation for mankind. Also, they might be left by human or alien colonialists who have left their planet. The reason for leaving might be that the planet could be too hot or cold, and this causes the situation, where they should leave to another star system. Maybe those colonists would stop only because they needed to repair their spaceships and then they were gone. If they would not close the robot factories property, those machines would be wake up and become a threat.


The intelligence doesn’t necessarily mean that some species are living. In real life, scientists are creating robots, what are looking like animals like bugs. Those new kind of robots are working independently, and they don’t need electricity for working property. Those animal-shaped robots could be equipped with fuel cells, what can make electricity using alcohol or another hydrocarbon. Those artificial bugs can be same sized than butterfly or dragonfly. In this scenario, the person might have this kind of robot for guarding the house. Artificial dragonfly can use alcohol like spree to create the electricity for its operations. When this small size robot needs refueling, it just flies to the plate, where is alcohol, and then it uses it in its fuel cells. The CIA would use this kind of vehicles for intelligence missions. In the wildest dreams, those small-sized robots could someday investigate the surface of the Saturnian giant moon Titan.This kind of devices can use the hydrocarbon from this moons seas.


The only thing what is needed is that in those chemical combinations have oxygen. It can be separated from the molecules by using the active carbon filter. If we are thinking about artificial intelligence and this kind of devices, we must understand, that they can continue their job even if their creators have been gone. This is the problem with interstellar space flight. If we will send the space probe with sophisticated Artificial Intelligence, this probe could become a new species, because in this scenario I will begin with the thing, that those interstellar probes have the capacity to fix themselves and make the copy of themselves. In this scenario, the artificial intelligence starts to develop itself, and because that probe has been traveled to another star maybe millions of years, the communication between Earth and this probe has been cut.


I sometimes have thought that what will happen to the probes, what have been traveled pass their target star. In the scenario, what British Interplanetary society have called “Project Daedalus” the massive probe would be sent to the Barnard Star, and the key element of this mission is that this space probe will fly past the star, and then it starts the orbital probe when it comes near the planetary system. Those probes of the future must be equipped by sophisticated artificial intelligence, what can find materials from the space to replace its structural damages. And it could also make copies of itself. The machine, what makes copies of itself is called as the “Von Neumann-machines”. When the probe has passed the star, the communication with Earth will be minimized. And then probe would lose contact with humans. This doesn’t mean that the artificial intelligence would stop working.


The nuclear reactors and other power devices are fully operational, and if the probe would travel in the space using self-sustain fusion power with the interstellar ramjet, this probe would continue its missions, and if the message from Earth would not come, this device may start to make copies of itself. In other scenarios, the civilization would build automatized factories on some planet. Those factories would make the machines and parts independently. And when this civilization would leave from this planet, they might forget to shut down their factory. If this factory can make product development and revolutionize the productions independently, it can be the begin for new species, what is actually a robot. The robot civilization would become the threat to other species because it might be felt necessary to colonize other planets.


The problem of the robots is that if they are programmed to protect their creators, who have passed away, the situation would turn violent. If they would not get any vision, of the creature, what was planned to protect, the robots would start next level of the program. And they would maybe think that their masters are dead. Robots would not have imagined. Robots do not apply anything. So in this scenarios, if the masters of those robots are gone, those machines don’t make any investigations like archeological digging, if they are not involved in their programs.


And if their masters are gone, would robots start the counterstrike. The counter strike would be limited to the normal situation. When somebody would hit against the masters of those robots, the counterstrike would be stopped by another master. But if there would be no masters of the system, would the counterstrike become the massacre. And in this scenario, those robots might start to build spaceships for continuing the strike, because the programmers of this machine would not prepare for the situation, where there are no masters of this system. And it can cause the robot invasion of another planet.

Sources:

https://en.wikipedia.org/wiki/Project_Daedalus

https://en.wikipedia.org/wiki/Bussard_ramjet

Picture 1.

http://www.daviddarling.info/images2/Bussard_ramjet_Mann.jpg

https://crisisofdemocracticstates.blogspot.fi/

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